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CURRENT PROJECT

Our Current project is to raise funds to benefit the breast cancer vaccine research of Dr. Brian Czerniecki of the Hospital of the University of Pennsylvania. His research is cutting edge, and we believe strongly in his vision.

 

Dr. Czerniecki is a highly recognized and respected oncological surgeon and researcher, who specializes in the least invasive means to treat breast cancer. He has had positive results in the first phase trial of his vaccine, which was funded by the National Institutes of Health (NIH). Our goal is to make certain he has the funds he needs for the next steps in his research.

 

Check out the links at the bottom of the page to learn more.

 

Contact information for the Phase 2 trial

A Randomized Trial of HER-2/neu Pulsed DC1 Vaccine for Patients with DCIS

For information please contact:

Jeanne Schueller, Research Project Manager, Department of Surgery

(office) 215-349-8399

(fax) 215-662-3179

jeanne.schueller@uphs.upenn.edu

CURRENT OPEN CLINICAL TRIALS

 

1. Pilot Phase I HER-2 Pulsed-DC Vaccine to Prevent Recurrence for Patients with
    HER-2 Driven High Risk Invasive Breast Cancer Post Neoadjuvant Chemotherapy

2. Pilot Phase I HER-2 Pulsed DC Vaccine to Prevent Recurrence for Patients with
    HER-2 Driven High Risk Invasive Breast Cancer

A Randomized Trial of HER-2/neu Pulsed DC1 Vaccine for Patients with DCIS

information on the 2nd phase of the Clinical Trial of Dr. Czerniecki's breast cancer vaccine research -  includes a description of the trial, and contact information for taking part in the trial

 

Based on the impressive success of the first phase of his clinical trial, Dr. Czerniecki and his staff at the University of Pennsylvania are excited to announce the 2nd phase clinical trial for a breast cancer vaccine.

 

This study involves using your own cells to develop a vaccine that will attack cancer and prevent it from growing. Upon entering the study, your blood will be drawn in a way that allows us to collect only your white blood cells. These cells will be used to create a vaccine, which you will receive weekly over a six-week period. After you receive the vaccine, you will undergo the standard surgical procedure to remove any remaining DCIS in the breast. Your doctor will stay actively involved throughout your trial participation.

 

The trial is open, and there are spots for patients available - if you have been diagnosed, or know someone who has been diagnosed, and have not yet had surgery - you might be eligible to participate in the trial.

 

The faster we fill the spots in the trial, the sooner progress can be reported,

and the sooner we move forward.

 

For information please contact:

Jeanne Schueller, Research Project Manager, Department of Surgery

(office) 215-349-8399

(fax) 215-662-3179

jeanne.schueller@uphs.upenn.edu

 

Jeanne can also put you in touch with lay volunteers who have knowledge of the vaccines. Please tell all your contacts about this, so that anyone diagnosed with breast cancer can find out if they are eligible for this trial prior to surgery!!!

 

Professional Biography of Dr. Brian Czerniecki    

information on Dr. Czerniecki and a description of his breast cancer vaccine research

 

OncoLink  Interview with Dr. Czerniecki 

interview from the first trial of the vaccine

 

Oncology Times  Dendritic Cell Vaccine Induces Strong Immune Response Against DCIS    

mention of the first trial and results - it is the fourth segment of the article (scroll down the page to read)

 

Cancer Review

Development of Vaccines for High-Risk Ductal Carcinoma In situ of the Breast  

 

Cancer Review

Targeting HER-2/neu in Early Breast Cancer Development Using Dendritic Cells with   Staged Interleukin-12 Burst Secretion

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