Taking the Olympic Approach to Solving Cancer.

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Pennies in Action was founded in 2007 by Olympic athlete, coach, and cancer survivor Uschi Keszler. Guided by its “Olympic Approach” to solving cancer, the organization has grown from a grassroots effort into a powerful patient-driven movement — amplified by the voices, stories, and support of the patients and families at the center of its mission. Through nearly two decades of advocacy and fundraising, Pennies in Action has helped support the advancement of Dr. Brian Czerniecki’s immunotherapy research from early-stage development toward treatments now impacting patients today, while continuing to build momentum toward a future without cancer.

Impact & Inspiration

At Pennies in Action, we channel scientific innovation and public generosity into transformative clinical advancements. Discover the roadmap guiding our future.

Our Mission

We support the continued groundbreaking research and application of Dr. Brian Czerniecki, MD, PhD and his team's non-toxic Dendritic Cell Immunotherapy, now treating Stage 4 cancer patients

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Our Vision

Through compassionate, hands on, and safe patient driven solutions, we aim to remove the threat of cancer one patient at a time so that one day all people will know a life without the deadly threat of the despicable disease called cancer.

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IMPACT IN MOTION

Find Your Way to Make a Difference.

Be a Champion for Change

From patients and families to the next generation of advocates, our ambassador programs bring people together to raise awareness, educate communities, and turn compassion into action.

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Come Together for a Cause

Join us at upcoming events that bring our community together to celebrate progress, share stories, and raise support for patients and innovative cancer research.

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Every Contribution Makes a Difference

Whether you make a one-time donation, join our Podium Club as a monthly supporter, or give anonymously through our Silent Donor program, there are many ways to support patients and advance innovative cancer immunotherapy research.

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Pioneering Cancer Immunotherapy

Funding the leaps that turn clinical trials into cures.

Backed by over 20 years of research and published clinical findings, this personalized immunotherapy uses patients’ own immune cells to activate a natural T-cell response against cancer, with promising patient outcomes and relatively low reported toxicity.

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REAL HOPE. REAL IMPACT.

The Right to Try. The Need for Action

For over 20 years, patients have been at the heart of our mission. Today, Pennies in Action is focused on helping women with stage 4 breast cancer who have exhausted standard treatment options access investigational immunotherapy through Right to Try. While these patients may be eligible to pursue treatment, many cannot afford to fund it themselves. That's where we come in, raising the funds needed to help make access possible.

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Patient Feature

How Pennies in Action Fueled Devon's Breakthrough

After receiving a Stage IV cancer diagnosis and facing limited treatment options, Devon Hoyt discovered Dr. Brian Czerniecki's innovative immunotherapy research. With support from Pennies in Action, Devon was able to access investigational treatment and now shares her journey of hope, perseverance, and the importance of expanding patient access to emerging cancer therapies. She is now cancer free 2 years from her diagnosis.

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Our Champions

Meet the original champions whose decades of dedication, advocacy, and research continue to drive the Pennies in Action mission forward.

Uschi Keszler

Founder, Olympian

Uschi Keszler is a former Olympic athlete, 6-time Olympic coach, and former U.S. Olympic Committee member. A survivor of tuberculosis, breast cancer, and uterine cancer, she founded Pennies in Action® Foundation I n 2007 with a singular mission: to help remove the threat of cancer in our lifetime. Driven by her “Olympic Approach”, Uschi’s goal is to push this promising cancer treatment across the finish line and win a Gold Medal for mankind.

Dr. Brian Czerniecki, MD, PhD

Lead Researcher, Breast Surgical Oncologist

Dr. Brian Czerniecki, MD, PhD is the leading pioneer of non-toxic Dendritic Cell Immunotherapy for cancer treatment, a groundbreaking approach that started with stage 0 patients, and has now achieved the milestone of treating Stage 4 cancer patients. As Chair of Breast Oncology at Moffitt Cancer Center and Professor Emeritus at the University of Pennsylvania, he brings decades of clinical and research expertise to the fight against cancer. With over 200 peer-reviewed publications and global recognition for his earlier development of sentinel lymph node mapping, Dr. Czerniecki focuses on transforming cancer treatment through the power of the immune system — without the devastating side effects of traditional therapies or auto-immune diseases from other types of immunotherapies.

Dr. Gary Koski, PhD

Lead Immunologist

Dr. Gary Koski, PhD is a veteran immunologist and professor at Kent State University, and a longtime research partner of Dr. Brian Czerniecki, dating back to their work together at the National Institutes of Health. As a key contributor to the development of Dendritic Cell Immunotherapy, Dr. Koski has played an essential role in advancing this non-toxic cancer treatment breakthrough.Dr. Koski was involved in numerous research projects over decades proving his scientific superiority in the field of research. His conservative yet hopeful and steady approach has been pivotal in the advancement of this therapy.